A randomized, double-blind, placebo-controlled study of light therapy for depression during pregnancy Posted by Admin on December 2014
Light, Cognition, Behaviour and Health.
Within the NWO call ‘Light, Cognition, Behaviour and Health’ Mijke van den Berg was granted a sum of 300k Euro from NWO and 100k Euro matching money by Philips for the project “A randomized, double-blink, placebo-controlled study of light therapy for depression during pregnancy”. This grant will provide Mijke the means to hire a PhD student and a part-time postdoc. See below for a description of the project.
Depression during pregnancy negatively affects pregnancy, birth outcome and child neurocognitive development. Since treatment with antidepressant medication
is controversial because of its unknown effects on intrauterine child development, alternative non-pharmacotherapeutical interventions are of high relevance.
Bright light therapy (BLT) has proven to be effective in depression, with few adverse reactions. Therefore, it is an attractive candidate treatment
for pregnant women with depression.
This study is a randomized, double-blind, placebo-controlled clinical trial comparing the antidepressive effects of BLT with placebo in 150 pregnant women with d epression. The primary aim of this study is to investigate whether BLT is an effective treatment for depression during pregnancy compared with low-intensity light therapy (placebo). Secondary aims of the study are to demonstrate the effect of BLT on sleep quality, endocrine function during pregnancy, and on delivery outcomes; if any of these effects are present, their mediating role on mother and child outcomes will be tested.